KPV

KPV – Research Use Only

Overview

KPV is a synthetic tripeptide composed of Lysine-Proline-Valine, derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH). It is commonly studied in vitro for its involvement in anti-inflammatory signaling pathways, immune modulation mechanisms, and melanocortin receptor interactions.

KPV is frequently utilized in laboratory models examining cytokine regulation, epithelial cell response, and inflammatory signaling modulation under controlled experimental conditions.

---

Background

KPV represents the 11–13 amino acid fragment of α-MSH, retaining specific signaling properties associated with melanocortin pathway interactions. In research environments, it has been explored for its potential influence on:

• Cytokine expression and regulation

• NF-κB–related inflammatory signaling pathways

• Immune response modulation

• Epithelial barrier function

• Melanocortin receptor activity

Due to its short peptide structure and defined sequence, KPV is well-suited for in vitro studies evaluating peptide-mediated inflammatory and immune signaling mechanisms.

---

Common Research Applications

• Studying cytokine regulation pathways

• Investigating melanocortin receptor signaling

• Exploring inflammatory response modulation

• Examining epithelial cell signaling mechanisms

• Evaluating immune system regulatory pathways

---

Product Specifications

Form: Lyophilized peptide (research formulation)

Contents: KPV (Lys-Pro-Val)

Size:

• 10 mg

Chemical Formula:

• C₁₆H₃₀N₄O₄

Molar Mass:

• 342.43 g/mol

CAS Number:

• 67727-97-3

PubChem CID:

• 125672

Synonyms:

• Lys-Pro-Val

• L-Valine, N-(1-L-lysyl-L-prolyl)-

• MSH (11–13)

• L-Lysyl-L-prolyl-L-valine

• Lysyl-prolyl-valine

• ACTH (11–13)

Shelf Life:

• 36 months (when stored under recommended conditions)

Storage:

• –20 °C recommended for long-term storage

Reconstitution:

• Sterile water (research-grade only)

Intended Use:

• For laboratory research use only