N-Acetyl-Semax Spray

N-Acetyl-Semax Spray – Research Use Only

Overview

N-Acetyl-Semax Spray contains a stabilized analog of the synthetic heptapeptide Semax, modified with an N-acetyl group to enhance molecular stability and resistance to enzymatic degradation. This formulation is intended for laboratory research exploring neurotrophic signaling, cognitive pathway regulation, and neurotransmitter modulation.

Semax analogs are widely studied for their interaction with brain-derived neurotrophic factor (BDNF) pathways, monoaminergic systems, and stress-response signaling networks.

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Background

Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–7) with structural modifications that remove hormonal activity while preserving neuroactive properties. The N-acetyl modification increases peptide stability and may prolong functional persistence in controlled research environments.

In laboratory studies, N-Acetyl-Semax is commonly examined for its potential involvement in:

• Neurotrophic factor regulation (including BDNF expression)

• Dopaminergic and serotonergic signaling pathways

• Cognitive performance and memory-related signaling

• Stress-response pathway modulation

• Neuroprotective signaling mechanisms

Researchers often investigate how Semax analogs influence synaptic plasticity and adaptive neural responses under experimental conditions.

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Common Research Applications

• Studying neurotrophic signaling pathways

• Exploring cognitive and memory-associated mechanisms

• Investigating monoamine neurotransmitter modulation

• Examining stress-response regulation

• Evaluating peptide stability enhancements in neuroactive compounds

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Product Specifications

Sequence: Ac-Met-Glu-His-Phe-Pro-Gly-Pro (N-Acetyl-Semax)

Molecular Formula: C₃₇H₅₁N₉O₁₀

Form: Liquid (intranasal research formulation)

Purity: ≥ 99% (HPLC)

Size: 5 mg

Concentration: 50 mcg per spray

Estimated Sprays Per Bottle: 100 sprays (standard metered delivery)

Storage: 2–8 °C recommended

Solubility: Water-soluble peptide (research-grade only)

Intended Use: For laboratory research use only