NAD +

NAD+ (Nicotinamide Adenine Dinucleotide) – Research Use Only

Overview

NAD+ is an essential coenzyme found in every living cell. It plays a major role in cellular energy production, metabolism, and overall cell function. Research commonly focuses on how NAD+ supports mitochondrial activity, helps regulate cellular repair processes, and influences pathways linked to aging and metabolic health. Because of these functions, NAD+ is widely used in studies exploring energy balance, DNA repair, and longevity biology.

---

Background

NAD⁺ works by switching between two forms, NAD+ (oxidized) and NADH (reduced), to help the cell transfer energy efficiently. It is a key part of the citric acid cycle and the electron transport chain, both of which power the cell.

Laboratory studies have shown that NAD+ levels naturally decline with stress and aging. This decline affects important pathways involving:

• Sirtuins (cellular health and longevity)

• PARPs (DNA repair)

• Mitochondrial function

Because of this, NAD+ restoration and supplementation are active areas of research in metabolism, neurology, and age-related biology.

---

Common Research Uses

• Studying cellular metabolism and mitochondrial energy production

• Exploring sirtuin and PARP enzyme pathways

• Investigating oxidative stress and DNA repair responses

---

Product Specifications

• Chemical Name: β-Nicotinamide Adenine Dinucleotide (oxidized form)

• Molecular Formula: C₂₁H₂₇N₇O₁₄P₂

• Molecular Weight: 663.4 g/mol

• Form: Lyophilized powder

• Purity: ≥ 99% (HPLC)

• Storage: –20 °C (long-term)

• Solubility: Sterile water or phosphate-buffered saline (PBS)