PT-141 – Research Use Only
Overview
PT-141 is a synthetic peptide derived from Melanotan II and functions as a melanocortin receptor agonist, with primary activity at MC3R and MC4R receptors. It is widely studied in laboratory research exploring neuroendocrine signaling pathways, central nervous system activity, and melanocortin-mediated receptor interactions.
Due to its receptor specificity, PT-141 is commonly utilized in experimental models investigating melanocortin pathway signaling and CNS-related regulatory mechanisms.
Background
PT-141 (Bremelanotide) is a synthetic melanocortin analog engineered to selectively interact with melanocortin receptors involved in neuroendocrine communication. In research environments, it is examined for its involvement in:
• MC3R and MC4R receptor activation
• Central nervous system signaling pathways
• Neuroendocrine regulatory mechanisms
• Hypothalamic signaling models
• Melanocortin receptor-binding dynamics
Because melanocortin receptors influence multiple regulatory systems within the body, PT-141 is frequently studied in laboratory settings evaluating receptor specificity, CNS pathway modulation, and peptide-receptor interaction models.
Common Research Applications
• Studying melanocortin receptor activation
• Investigating neuroendocrine signaling pathways
• Exploring CNS-mediated regulatory mechanisms
• Examining receptor-binding specificity models
• Evaluating melanocortin pathway dynamics
Product Specifications
Form: Lyophilized peptide (research formulation)
Contents: PT-141
Size:
• 10 mg
Chemical Formula:
• C₅₀H₆₈N₁₄O₁₀
Molar Mass:
• 1025.2 g/mol
CAS Number:
• 189691-06-3
PubChem CID:
• 9941379
Synonyms:
• Bremelanotide
• Vyleesi
• CHEMBL2070241
Shelf Life:
• 36 months (when stored under recommended conditions)
Storage:
• –20 °C recommended for long-term storage
Reconstitution:
• Sterile water (research-grade only)
Intended Use:
• For laboratory research use only





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